Mediastinal Castleman Hastalığı: İki Olgu Sunumu ve Literatürün Gözden Geçirilmesi

Abstract

Castleman hastalığı, yaş ve cinsiyetten bağımsız olarak görülen lenf nodlarının aşırı büyümesidir. Kliniğimizde cerrahi olarak tedavi edilen ve histopatolojik inceleme sonunda Castleman hastalığı tanısı alan 37 yaşında kadın ve 38 yaşında erkek olgular tartışılmaktadır. Her iki hastaya da tanısal torakotomi yapılarak kitleler rezeke edilmiş ve patoloji sonuçları hyaline-vasküler tipte Castleman hastalığı olarak bildirilmiştir. Olgular halen takip altında ve asemptomatiktirler. Castleman's disease is an enlargement of lymph nodes without differentiaton of age and sex. A 37-year-old woman and a 38-year-old man patients were treated surgically in our clinic who were diagnosed as Castleman's disease with histopathological examination. For both of the patients diagnostic thoracotomy was performed and tumoral masses were resected. Postoperatively, hyaline-vascularized type Castleman's disease was diagnosed and our patients were remained asymptomatic at follow-up. Our patients were remained asymptomatic for follow-up after operation.