BAYRAM, ERHAN; TOPÇU, YASEMİN; AKINCI, GÜLÇİN; ÇAKMAKÇI, HANDAN; ARSLAN, NUR; HIZ KURUL, AYŞE SEMRA
(Dokuz Eylül Üniversitesi Tıp Fakültesi, 2012)
Tay-Sachs is a neurodegenerative lysosomal storage disease that is caused by the mutations in the HEXA gene. Decreased ß-hexosaminidase A activity leads to the accumulation of the GM2 gangliosides in neuron cytoplasms ...